OSW-1 analogues: Modification of the carbohydrate moiety

4 OSW-1 analogues featuring modified carbohydrate moieties were prepared. The purpose of these modifications was to assess the importance of certain chemical functions with respect to biological activity. The synthesis and biological activity of the target molecules are shown.

Four new OSW-1 analogues with modified disaccharide moieties were synthesized and their cytotoxic activity against a range of cell lines was evaluated.Figure optionsDownload as PowerPoint slide