Synthesis, characterization, antibacterial activity, and interaction with DNA of the vanadyl-enrofloxacin complex

The neutral mononuclear vanadyl complex with the quinolone antibacterial drug enrofloxacin has been prepared and characterized with physicochemical and spectroscopic techniques and molecular mechanics calculations. The interaction of the complex with calf-thymus DNA has also been investigated and the antimicrobial activity has been evaluated against three different microorganisms.

The synthesis, characterization, antimicrobial activity and interaction with calf-thymus DNA of the mononuclear vanadyl complex with the second-generation quinolone enrofloxacin are reported.Figure optionsDownload as PowerPoint slide