کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1378174 981995 2010 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Biodegradable MPEG-g-Chitosan and methoxy poly(ethylene glycol)-b-poly(ε-caprolactone) composite films: Part 1. Preparation and characterization
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Biodegradable MPEG-g-Chitosan and methoxy poly(ethylene glycol)-b-poly(ε-caprolactone) composite films: Part 1. Preparation and characterization
چکیده انگلیسی

In this paper, composite films of MPEG-g-Chitosan (MPEG-g-CS) and methoxy poly(ethylene glycol)-b-poly(ε-caprolactone) (MPEG-b-PCL) were prepared by casting/solvent evaporation method. MPEG-b-PCL was synthesized by ring-opening polymerization of ε-caprolactone initiated by MPEG (Mn = 2000). And MPEG-g-CS was synthesized by alkylation of chitosan followed by Schiff base formation. Characterization of composite films was performed by fourier transform infrared spectroscopy (FTIR), differential scanning calorimeter (DSC), thermogravimetric analysis (TGA) and scanning electron microscopy (SEM). Chemical composition of composite film had strongly influenced the thermal properties, morphology, water absorption and in vitro degradation behavior of films. With the increase of MPEG-g-CS content in composite films, the water absorption and degradation rate increased accordingly. The composite films based on MPEG-g-CS and MPEG-b-PCL prepared in this work might have great potential in the application of wound healing and tissue engineering.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 79, Issue 2, 20 January 2010, Pages 429–436
نویسندگان
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