Synthesis and antifungal activity of 5-arylamino-4,7-dioxobenzo[b]thiophenes

5-Arylamino-4,7-dioxobenzo[b]thiophenes were synthesized and tested for in vitro antifungal activity against Candida species and Aspergillus niger. Among them, 5-arylamino-6-chloro-2-(methoxycarbonyl)-4,7-dioxobenzo[b]thiophenes exhibited potent antifungal activity against Candida species.