کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1379222 | 982022 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Two methylene groups in phospholipids distinguish between apoptosis and necrosis for tumor cells
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
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چکیده انگلیسی
High inhibitory effects of hybrid liposomes (HL) themselves composed of DMPC/10 mol % C12(EO)23 on the growth of HL-60 cells were obtained without any drug. Induction of apoptosis was obtained by the HL of DMPC/10 mol % C12(EO)23. On the other hand, necrosis was observed for the HL of DLPC/10 mol % C12(EO)23. In the case of DPPC/10 mol % C12(EO)23, neither apoptosis nor necrosis was observed.
It was found that two methylene groups in phospholipids having the same head group could clearly distinguish between apoptosis and necrosis for human leukemia cells.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 16, Issue 4, 15 February 2006, Pages 782–785
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 16, Issue 4, 15 February 2006, Pages 782–785
نویسندگان
Hideaki Nagami, Koji Nakano, Hideaki Ichihara, Yoko Matsumoto, Ryuichi Ueoka,