کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1384549 | 982408 | 2010 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and characterization of biodegradable pH-sensitive hydrogel based on poly(ε-caprolactone), methacrylic acid, and Pluronic (L35)
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis and characterization of biodegradable pH-sensitive hydrogel based on poly(ε-caprolactone), methacrylic acid, and Pluronic (L35) Synthesis and characterization of biodegradable pH-sensitive hydrogel based on poly(ε-caprolactone), methacrylic acid, and Pluronic (L35)](/preview/png/1384549.png)
چکیده انگلیسی
A series of biodegradable and pH-sensitive hydrogels based on poly(ε-caprolactone) (PCL), Pluronic, and methylacrylic acid (MAA) were successfully prepared by UV-initiated free radical polymerization, which were further characterized by 1H NMR and FTIR. Swelling behavior in different aqueous media and pH-responsibility of the hydrogels were studied in detail. With increase in pH value of aqueous media from 1.2 to 7.2, swelling ratio of the hydrogels increased accordingly. The hydrolytic degradation behavior of these hydrogels was also investigated in detail. The biodegradable pH-sensitive hydrogel obtained in this work might have great potential application in drug delivery system.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 79, Issue 3, 11 February 2010, Pages 755–761
Journal: Carbohydrate Polymers - Volume 79, Issue 3, 11 February 2010, Pages 755–761
نویسندگان
Ke Wang, Xu Xu, TingTing Liu, ShaoZhi Fu, Gang Guo, YingChun Gu, Feng Luo, Xia Zhao, YuQuan Wei, ZhiYong Qian,