کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1385197 | 982435 | 2006 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Conversion of crystal structure of the chitin to facilitate preparation of a 6-carboxychitin with moisture absorption–retention abilities Conversion of crystal structure of the chitin to facilitate preparation of a 6-carboxychitin with moisture absorption–retention abilities](/preview/png/1385197.png)
Chitin has been subjected to regiospecific oxidation at C-6 with NaOCl in the presence of 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO) and NaBr at room temperature in aqueous solution to yield fully soluble 6-carboxychitin. Several physical and chemical pretreatments of the original chitin changed its crystal structure from α to β. After this pretreatment of the chitin the oxidation was easier to effect and the yield was greatly increased from 36% to 97% and the molecular weight was about 4 × 104 which was ca. 8 times that from the unpretreated chitin. Infrared spectroscopy (IR), X-ray diffraction, 13C NMR and solid-state NMR measurements, and thermal analysis techniques were used to characterize their molecular structures. The moisture absorption and retention abilities of these types of compounds were compared with those of sodium hyaluronan and carboxymethyl chitosan (CMCS) and were found to be superior. They therefore have the potential to substitute for hyaluronan for use in cosmetics and clinical medicine fields.
Journal: Carbohydrate Polymers - Volume 66, Issue 2, 27 October 2006, Pages 168–175