کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1385279 | 982440 | 2011 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Anionic polysaccharide hydrogels with thermosensitive properties
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
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چکیده انگلیسی
Microparticles of crosslinked carboxymethyl pullulan were chemically modified by introducing hydrophobic thermosensitive Poloxamer groups; these new pullulan derivatives are expected to present, besides their ionic character, both amphiphilic and thermosensitive properties. The obtained microparticles were physico-chemically characterized and their interaction with various proteins, such as enzymes (lysozyme, BSA), vaccines (tetanus anatoxin), was studied. The retention/release behavior of the biomolecules on/from the studied derivatives is influenced by electrostatic and hydrophobic forces, as well as by the presence of thermosensitive Poloxamer groups.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 83, Issue 1, 1 January 2011, Pages 52–59
Journal: Carbohydrate Polymers - Volume 83, Issue 1, 1 January 2011, Pages 52–59
نویسندگان
Georgeta Mocanu, Doina Mihaï, Virginie Dulong, Luc Picton, Didier Le Cerf, Misu Moscovici,