کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1385279 982440 2011 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Anionic polysaccharide hydrogels with thermosensitive properties
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Anionic polysaccharide hydrogels with thermosensitive properties
چکیده انگلیسی

Microparticles of crosslinked carboxymethyl pullulan were chemically modified by introducing hydrophobic thermosensitive Poloxamer groups; these new pullulan derivatives are expected to present, besides their ionic character, both amphiphilic and thermosensitive properties. The obtained microparticles were physico-chemically characterized and their interaction with various proteins, such as enzymes (lysozyme, BSA), vaccines (tetanus anatoxin), was studied. The retention/release behavior of the biomolecules on/from the studied derivatives is influenced by electrostatic and hydrophobic forces, as well as by the presence of thermosensitive Poloxamer groups.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 83, Issue 1, 1 January 2011, Pages 52–59
نویسندگان
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