کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1385719 982456 2006 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis of asparagine-linked bacillosamine
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Synthesis of asparagine-linked bacillosamine
چکیده انگلیسی

Various types of protein glycosylation have been identified from prokaryotes. Recent investigations have revealed the presence of N-linked glycoproteins in the pathogenic bacterium, Campylobacter jejuni. The structure of this glycan is unique, consisting of 5 GalNAc and 1 Glc, in addition to 2,4-diacetamido-2,4,6-trideoxy-d-glucopyranose (bacillosamine; Bac), which is N-glycosidically linked to the side chain of asparagine (Asn). We synthesized Bac from a 2-azido-2-deoxy-d-galactose derivative, which was further converted to the Asn-linked form.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Research - Volume 341, Issue 11, 14 August 2006, Pages 1922–1929
نویسندگان
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