کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1386085 | 982471 | 2006 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Full assignment of the 1H and 13C spectra and revision of the O-acetylation site of the capsular polysaccharide of Streptococcus pneumoniae Type 33F, a component of the current pneumococcal polysaccharide vaccine Full assignment of the 1H and 13C spectra and revision of the O-acetylation site of the capsular polysaccharide of Streptococcus pneumoniae Type 33F, a component of the current pneumococcal polysaccharide vaccine](/preview/png/1386085.png)
The structure of the capsular polysaccharide from Streptococcus pneumoniae Type 33F was originally determined by a combination of chemical methods and limited use of NMR spectroscopy [Can. J. Biochem. Cell Biol.1984, 62, 666–677]. We report full 1H and 13C assignments and confirm the structure of the saccharide repeat unit, but find that the site of O-acetylation is O-2 of the →5)-β-d-Galf, rather than the →3)-β-d-Galf residue. We find that a slightly higher percentage of the repeat units are O-acetylated:
Full NMR assignments and a revised location for the O-acetyl group in the capsular polysaccharide from Streptococcus pneumoniae Type 33F are reported. The O-acetyl group is attached to O-2 of the →5)-β-d-Galf residue, rather than the →3)-β-d-Galf as previously reported.Figure optionsDownload as PowerPoint slide
Journal: Carbohydrate Research - Volume 341, Issue 1, 16 January 2006, Pages 68–74