کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1386153 982476 2009 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Polyphenolic-polysaccharide compounds from selected medicinal plants of Asteraceae and Rosaceae families: Chemical characterization and blood anticoagulant activity
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Polyphenolic-polysaccharide compounds from selected medicinal plants of Asteraceae and Rosaceae families: Chemical characterization and blood anticoagulant activity
چکیده انگلیسی

The preparations from selected traditional medicinal plants in Poland (Asteraceae and Rosaceae families), were prepared in the multi-step process of isolation and their anticoagulant activity was measured by APTT and PT tests. The most promising effect was observed for the substances extracted from Fragaria vesca (Rosaceae) and Echinacea purpurea (Asteraceae). They showed interesting activity with respect to the activity of 5th International Standard for Unfractionated Heparin in APTT method. The structure characterization by IR, HPLC, GLC-MS and colorimetric methods revealed that these preparations are macromolecular polysaccharide–polyphenolic conjugates, similar to cell wall acidic macromolecular fragments which are common in the higher plants. The high content of hexuronic acids, as well as phenolic glycoconjugates seems to be responsible for the observed anticoagulant activity.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 77, Issue 3, 11 July 2009, Pages 568–575
نویسندگان
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