کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1387231 | 982560 | 2010 | 7 صفحه PDF | دانلود رایگان |
We developed novel β-chitin/nanosilver composite scaffolds for wound healing applications using β-chitin hydrogel with silver nanoparticles. The prepared nanosilver particles and nanocomposite scaffolds were characterized using SEM, FT-IR, XRD and TGA studies. The antibacterial, blood-clotting, swelling, cell attachment and cytotoxicity studies of the prepared composite scaffolds were evaluated. The prepared β-chitin/nanosilver composite scaffolds were bactericidal against Escherichia coli and Staphylococcus aureus and it showed good blood-clotting ability as well. Cell attachment studies using vero (epithelial) cells showed that the cells were well attached on the scaffolds. These results suggested that β-chitin/nanosilver composite scaffold could be a promising candidate for wound dressing applications.
Journal: Carbohydrate Polymers - Volume 80, Issue 3, 5 May 2010, Pages 761–767