کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1387900 1500863 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Elucidation of the structure of the oligosaccharide from wild type Moraxella bovis Epp63 lipooligosaccharide
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Elucidation of the structure of the oligosaccharide from wild type Moraxella bovis Epp63 lipooligosaccharide
چکیده انگلیسی


• Wild type Moraxella bovis Epp63 lacks O-antigen.
• Wild type M. bovis Epp63 OS is branched and contains 10 sugars in addition to Kdo.
• M. bovis Epp63 OS has a terminal (1S)-GalaNAc →4,6-linked to a sub-terminal Gal.
• Wild type M. bovis Epp63 core oligosaccharide lacks heptose.

Moraxella bovis is a Gram-negative microorganism that causes Infectious Bovine Keratoconjunctivitis (IBK), colloquially known as ‘Pink eye’ in cattle worldwide. Lipopolysaccharides/lipooligosaccharides are the predominant glycans on the surface of Gram-negative microorganisms. Structural elucidation of the oligosaccharide structure of the rough phenotype of Moraxella bovis strain Epp63 was determined using GC–MS, methylation analysis, and NMR spectroscopy. The oligosaccharide is a branched structure that comprises 10 sugars in addition to KDO. The unusual features of this oligosaccharide include the fact that the oligosaccharide is devoid of heptose. The KDO residue is directly attached to a (→4,6)-branched glucose and additionally contains a terminal open chain acetal-linked N-acetylgalactosamine, (1S)-GalaNAc residue →4,6-linked to a sub-terminal galactose residue.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Research - Volume 388, 31 March 2014, Pages 81–86
نویسندگان
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