Efficiency of organic solvents on the ability of α2,3-sialyltransferase from Photobacterium sp. JT-ISH-224 to control a hydrolysis side reaction

► α2,3-Sialyltransferase (JT-ISH-224) possesses also sialidase activity. ► The enzyme was even active in the presence of water-soluble organic solvents. ► Water-soluble organic solvents mean acetonitrile, ethanol, methanol, or acetone. ► Only sialyltransferase activity was allowed in the presence of the organic solvents.