کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1388426 | 982793 | 2008 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and CD structural studies of CD52 peptides and glycopeptides
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis and CD structural studies of CD52 peptides and glycopeptides Synthesis and CD structural studies of CD52 peptides and glycopeptides](/preview/png/1388426.png)
چکیده انگلیسی
The syntheses of five natural and N-terminal acetylated peptides and glycopeptides of the CD52 antigen are described. Solid phase peptide synthesis was employed in the construction of the target compounds from Fmoc-protected commercial amino acids and synthetic glycan–asparagine conjugates. Circular dichroism studies of the synthetic targets showed that they exist as random coils in solution, and no significant change in secondary structure was observed when the CD52 peptide was either acetylated at the N-terminus or glycosylated at the Asn3 residue with a disaccharide or a fucose-containing branched trisaccharide.
Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Research - Volume 343, Issue 17, 24 November 2008, Pages 2894–2902
Journal: Carbohydrate Research - Volume 343, Issue 17, 24 November 2008, Pages 2894–2902
نویسندگان
Benjamin M. Swarts, Yu-Cheng Chang, Honggang Hu, Zhongwu Guo,