کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1388534 | 982801 | 2010 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Total synthesis of caminoside B, a novel antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The first total synthesis of caminoside B, a novel marine antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia, was developed. This marine small molecule inhibitor (IC50 = 20 μM) targeting type III secretory pathway of bacterial pathogenesis was assembled in good yield via a ‘2+2+1’ strategy based on stereocontrolled construction of the four glycosidic linkages.
The first total synthesis of caminoside B was developed via a ‘2+2+1’ strategy based on stereocontrolled construction of the four glycosidic linkages.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Research - Volume 345, Issue 6, 19 April 2010, Pages 750–760
Journal: Carbohydrate Research - Volume 345, Issue 6, 19 April 2010, Pages 750–760
نویسندگان
Zaihong Zhang, Chengli Zong, Gaopeng Song, Guokai Lv, Yuexing Chun, Peng Wang, Ning Ding, Yingxia Li,