Synthesis of spacer-containing analogs of serogroup 6 pneumococcal oligosaccharides

An efficient convergent strategy for the synthesis of a range of spacer-containing pneumococcal oligosaccharides of serogroup 6 and derivatives thereof has been developed. The spacer-containing oligosaccharides were deprotected and are available for subsequent conjugation and immunological studies, which are underway in our laboratory.

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