کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1388963 982833 2012 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Convenient strategies for the synthesis of 1,4-phenylene spaced sugars
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Convenient strategies for the synthesis of 1,4-phenylene spaced sugars
چکیده انگلیسی

Two synthetic strategies have been developed for the synthesis of spaced sugars with lipophilic 1,4-phenylene core. A building block combining the usefulness of Weinreb amide functionality and modified Julia olefination reaction has been explored towards this objective. This building block offers complete flexibility in attaching any desired sugar derivative across phenylene spacer via C–C bond formation. The other strategy uses carbohydrate based building blocks for the synthesis of symmetrical as well as unsymmetrical 1,4-phenylene spaced sugars. This is the first report for the synthesis of 1,4-phenylene spaced sugars via C–C bond formation.

Figure optionsDownload as PowerPoint slideHighlights
► Synthesis of hitherto unreported 1,4-phenylene spaced sugars has been achieved.
► The strategies have versatility to synthesize symmetrical and unsymmetrical varieties.
► Convenience of Weinreb amide group and modified Julia reaction has been used.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Research - Volume 347, Issue 1, 10 January 2012, Pages 55–63
نویسندگان
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