Conformational preferences in diglycosyl disulfides: NMR and molecular modeling studies

► Conformations of diglycosyl disulfides were studied by NMR and computations. ► The disulfide torsion angles (Ψ) are close to +90o or −90o (+g or −g). ► Up to four conformational regions around Φ and Ω are allowed for each Ψ values. ► No significant intramolecular hydrogen bonds were revealed in DMSO solution.