کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1389371 | 982869 | 2010 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis, characterization, and cytotoxicity of some novel glycosyl thiazol-2-imines as antitumoral agents
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis, characterization, and cytotoxicity of some novel glycosyl thiazol-2-imines as antitumoral agents Synthesis, characterization, and cytotoxicity of some novel glycosyl thiazol-2-imines as antitumoral agents](/preview/png/1389371.png)
چکیده انگلیسی
A series of novel glycosyl thiazol-2-imines (3a–g) have been synthesized regioselectively in good yields from the hydrolysis of thiazol-2(3H)-imine-linked glycoconjugates. The glycosyl thiazol-2-imines were evaluated for their antitumor activity against Hela (cervical carcinoma), HCT-8 (colon carcinoma) and Bel-7402 (liver carcinoma). Among the compounds screened, 1-benzoyl-4-(4-nitrophenyl)-3-β-d-glucopyranosyl-thiazol-2(3H)-imine (3c) was found to be the most active compound against HCT-8.
Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Research - Volume 345, Issue 3, 11 February 2010, Pages 437–441
Journal: Carbohydrate Research - Volume 345, Issue 3, 11 February 2010, Pages 437–441
نویسندگان
Qing Zhao, Chao Shen, Hui Zheng, Jinchao Zhang, Pengfei Zhang,