کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1389490 | 982887 | 2006 | 6 صفحه PDF | دانلود رایگان |
The structures of a series of large oligosaccharides derived from acharan sulfate were characterized. Acharan sulfate is an unusual glycosaminoglycan isolated from the giant African snail, Achatina fulica. Oligosaccharides from decasaccharide to hexadecasaccharide were enzymatically prepared using heparin lyase II and purified. Capillary electrophoresis and gel electrophoresis confirmed the purity of these oligosaccharides. Their structures, determined by ESI-MS and NMR, were consistent with the major repeating sequence in acharan sulfate, →4)-α-d-GlcNpAc-(1→4)-α-l-IdoAp2S-(1→, terminated by 4-linked α-d-GlcNpAc residue at the reducing end and by 4,5-unsaturated pyranosyluronic acid 2-sulfate at the non-reducing end.
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Journal: Carbohydrate Research - Volume 341, Issue 7, 22 May 2006, Pages 864–869