A facile synthesis of the GalNAcβ1→4Gal target sequence of respiratory pathogens

The carbohydrate sequence, GalNAcβ1→4Gal, is the target for the adhesion of several respiratory pathogens. The sequence was prepared in an optimized synthesis in forms that allow conjugation to scaffolds or surfaces.

An optimized synthesis of the carbohydrate sequence GalNAcβ1→4Gal is reported. This is the target sequence for the adhesion of several respiratory pathogens.Figure optionsDownload as PowerPoint slide