Preparation of synthetic oligosaccharide-conjugates of poly-β-(1→6)-N-acetyl glucosamine

- The synthesis of di-, tetra- and hexasaccharide fragments of PNAG was achieved.
- The resulted oligosaccharides were covalently attached to BSA by reductive amination.
- Two different hapten/BSA ratios were applied for disaccharide and tetrasaccharide.
- For study of influence of chain length hexasaccharide conjugate was also prepared.