gem-Difluoro-carbasugars, the cases of mannopyranose and galactopyranose

5a-Difluoro-5a-carbamannopyranose (gem-difluoro-carbamannopyranose) and 5a-difluoro-5a-carbagalactopyranose (gem-difluoro-carbagalactopyranose), close congeners of their respective natural sugars, in which the endocyclic oxygen atom has been replaced by a gem-difluoromethylene group, were synthesized from d-mannose and d-galactose, using a rearrangement strategy.

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