کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1390857 983152 2007 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Efficient synthesis of ω-mercaptoalkyl 1,2-trans-glycosides from sugar peracetates
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Efficient synthesis of ω-mercaptoalkyl 1,2-trans-glycosides from sugar peracetates
چکیده انگلیسی

Lewis acid-promoted reactions of peracetylated sugars (glucose, galactose, maltose, lactose) with ω-bromo-1-alkanols (C8, C12) were investigated. ZnCl2 was found to promote the 1,2-trans-glycosylation of the alcohols in toluene at about 60 °C in a stereocontrolled manner with better yields than commonly employed promoters such as SnCl4. The ω-bromoalkyl acetylated glycosides were readily converted to ω-mercaptoalkyl glycosides, which are useful for the preparation of glycoclusters.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Research - Volume 342, Issue 8, 11 June 2007, Pages 1009–1020
نویسندگان
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