کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1390972 | 983172 | 2006 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Studies on the α-(1â4)- and α-(1â8)-fucosylation of sialic acid for the total assembly of the glycan portions of complex HPG-series gangliosides
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Studies on the α-(1â4)- and α-(1â8)-fucosylation of sialic acid for the total assembly of the glycan portions of complex HPG-series gangliosides Studies on the α-(1â4)- and α-(1â8)-fucosylation of sialic acid for the total assembly of the glycan portions of complex HPG-series gangliosides](/preview/png/1390972.png)
چکیده انگلیسی
A synthetic study on α-(1â4) and α-(1â8)-fucosylation of sialic acid is reported, with the ultimate aim being the total assembly of the glycan portion of HPG-series gangliosides. In both types of fucosylations, the combination of a phenylthio fucosyl donor and a 1,5-lactamized acceptor provided high-yielding glycosylations to afford α-fucosyl-sialic acid sequences. The obtained α-Fucp-(1â8)-NeupNAc glycan having a 1,5-lactam bridge has been successfully transformed into the corresponding glycosyl donor.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Research - Volume 341, Issue 10, 24 July 2006, Pages 1522-1532
Journal: Carbohydrate Research - Volume 341, Issue 10, 24 July 2006, Pages 1522-1532
نویسندگان
Hiromune Ando, Hiroyo Shimizu, Yukari Katano, Yusuke Koike, Sachiko Koizumi, Hideharu Ishida, Makoto Kiso,