کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1390980 983172 2006 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis of a set of sulfated and/or phosphorylated oligosaccharide derivatives from the carbohydrate–protein linkage region of proteoglycans
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Synthesis of a set of sulfated and/or phosphorylated oligosaccharide derivatives from the carbohydrate–protein linkage region of proteoglycans
چکیده انگلیسی

The synthesis of a set of various sulfoforms and/or phosphoforms as 7-methoxy-2-naphthyl glycosides of β-d-Xylp, β-d-Galp-(1→4)-β-d-Xylp, and β-d-Galp-(1→3)-β-d-Galp-(1→4)-β-d-Xylp, structures encountered in the common carbohydrate–protein linkage region of proteoglycans, is reported for the first time. These molecules will serve as probes for systematic studies of the substrate specificity of the glycosyltransferases involved in the early steps of the biosynthesis of proteoglycans. A straightforward divergent preparation was achieved using key intermediates, which were designed as common precursors.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Research - Volume 341, Issue 10, 24 July 2006, Pages 1630–1644
نویسندگان
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