کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
141947 162950 2009 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The Neurocircuitry of Impaired Insight in Drug Addiction
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب شناختی
پیش نمایش صفحه اول مقاله
The Neurocircuitry of Impaired Insight in Drug Addiction
چکیده انگلیسی

More than 80% of addicted individuals fail to seek treatment, which might reflect impairments in recognition of severity of disorder. Considered by some as intentional deception, such ‘denial’ might instead reflect dysfunction of brain networks subserving insight and self-awareness. Here we review the scant literature on insight in addiction and integrate this perspective with the role of: (i) the insula in interoception, self-awareness and drug craving; (ii) the anterior cingulate in behavioral monitoring and response selection (relevant to disadvantageous choices in addiction); (iii) the dorsal striatum in automatic habit formation; and (iv) drug-related stimuli that predict emotional behavior in addicted individuals, even without conscious awareness. We discuss implications for clinical treatment including the design of interventions to improve insight into illness severity in addiction.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 13, Issue 9, September 2009, Pages 372–380
نویسندگان
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