Application of N-doped graphene modified carbon ionic liquid electrode for direct electrochemistry of hemoglobin

• Nitrogen-doped graphene (NG) was synthesized by a solvothermal method.
• NG was used for the investigation on direct electrochemistry of hemoglobin with carbon ionic liquid electrode.
• The Hb modified electrode exhibited excellent electrocatalytic activity toward different substrates.

Nitrogen-doped graphene (NG) was synthesized and used for the investigation on direct electrochemistry of hemoglobin (Hb) with a carbon ionic liquid electrode as the substrate electrode. Due to specific characteristics of NG such as excellent electrocatalytic property and large surface area, direct electron transfer of Hb was realized with enhanced electrochemical responses appearing. Electrochemical behaviors of Hb on the NG modified electrode were carefully investigated with the electrochemical parameters calculated. The Hb modified electrode exhibited excellent electrocatalytic reduction activity toward different substrates, such as trichloroacetic acid and H2O2, with wider dynamic range and lower detection limit. These findings show that NG can be used for the preparation of chemically modified electrodes with improved performance and has potential applications in electrochemical sensing.

The utilization of N-doped graphene enables direct electrochemistry of hemoglobin with a pair of well-defined redox peaks appearing.Figure optionsDownload as PowerPoint slide