کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1430716 987208 2009 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Electrospun nanofibers composed of poly(ε-caprolactone) and polyethylenimine for tissue engineering applications
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد بیومتریال
پیش نمایش صفحه اول مقاله
Electrospun nanofibers composed of poly(ε-caprolactone) and polyethylenimine for tissue engineering applications
چکیده انگلیسی

Poly(ε-caprolactone) (PCL) electrospun nanofibers have been reported as a scaffold for tissue engineering application. However, high hydrophobicity of PCL limits use of functional scaffold. In this study, PCL/polyethylenimine (PEI) blend electrospun nanofibers were prepared to overcome the limitation of PCL ones because the PEI as a cationic polymer can increase cell adhesion and can improve the electrospinnability of PCL. The structure, mechanical properties and biological activity of the PCL/PEI electrospun nanofibers were studied. The diameters of the PCL/PEI nanofibers ranged from 150.4 ± 33 to 220.4 ± 32 nm. The PCL/PEI nanofibers showed suitable mechanical properties with adequate porosity and increased hydrophilic behavior. The cell adhesion and cell proliferation of PCL nanofibers were increased by blending with PEI due to the hydrophilic properties of PEI.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 29, Issue 5, 1 June 2009, Pages 1725–1731
نویسندگان
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