کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1460370 989604 2015 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A new insight into biomedical applications of an apatite like oxyphosphate – BiCa4(PO4)3O
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد سرامیک و کامپوزیت
پیش نمایش صفحه اول مقاله
A new insight into biomedical applications of an apatite like oxyphosphate – BiCa4(PO4)3O
چکیده انگلیسی


• Synthesized compounds were pure and crystalline.
• Antimicrobial activity against E.coli, S.aureus and C.albicans were studied by spread plate method.
• Copper substitution enhanced the antimicrobial activity of the oxyapatite.
• All compounds were non-cytotoxic except manganese and zinc substituted oxyapatite.

Divalent ion (Cu, Co, Mn, Mg and Zn) substituted BiCa4(PO4)3O (BCPO) – an apatite like oxyphosphate is synthesized by conventional high temperature solid state method and characterized by powder X-ray diffraction (XRD), Fourier Transform infrared spectroscopy (FT-IR), Thermogravimetric analysis (TGA), Scanning electron microscope (SEM) and Energy dispersive X-ray spectroscopy (EDAX). Antimicrobial properties of these synthesized materials are studied by spread plate method against the three organisms E.coli, S.aureus, and C.albicans. It is noticed from the results that Copper substitution improved the antibacterial activity of the oxyapatite compared to other divalent ion substitution. Cytotoxicity study is carried out by MTT assay method against fibroblast NIH 3T3 cell line. All the synthesized compounds are non-cytotoxic except Mn(II) and Zn(II) substituted oxyapatite.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ceramics International - Volume 41, Issue 3, Part B, April 2015, Pages 4852–4860
نویسندگان
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