کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
146496 | 456371 | 2015 | 8 صفحه PDF | دانلود رایگان |
• Successful encapsulation of biocides in silica nanocapsules.
• Expedite and real-time screening method to assess the inactivation of bacteria.
• Antibacterial activity of silica nanocapsules loaded with biocides.
• The developed nanomaterials show high potential to be used in antifouling coatings.
This work reports the synthesis and characterization of silica nanocapsules with biologically-active compounds 2-mercaptobenzothiazole and 4,5-dichloro-2-octyl-4-isothiazolin-3-one. The resulting particles were characterized by scanning electron microscopy, thermogravimetry and adsorption–desorption isotherms of N2. The antibacterial activity was assessed for both nanocapsules dispersed in solution as well as incorporated in coating systems, using a recombinant bioluminescent Escherichia coli expressing the luxCDABE genes from the marine bioluminescent bacterium Aliivibrio fischeri. The decrease in light emission of the bacterial model, indicative as decrease of metabolic activity, was directly correlated with the level of biocide detected in solution by UV–Visible spectrophotometry. The results show that the developed nanomaterials show great potential for application in antifouling coatings.
Journal: Chemical Engineering Journal - Volume 270, 15 June 2015, Pages 150–157