کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1533 85 2009 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effect of surface structure on protein adsorption to biphasic calcium-phosphate ceramics in vitro and in vivo
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Effect of surface structure on protein adsorption to biphasic calcium-phosphate ceramics in vitro and in vivo
چکیده انگلیسی

Protein adsorption affects the function of cells and determines the bioactivity of biomaterial implants. Surface structure and properties of materials determine the behavior of protein adsorption. In the present study, two biphasic calcium-phosphate ceramics (BCPs) with different surface structures were fabricated by pressing and H2O2 foaming methods. Their surface characteristics were analyzed and the in vitro and in vivo protein adsorption on them was investigated. Porous BCP showed higher ability to adsorb proteins, and transforming growth factor-β1 (TGF-β1) adsorption notably increased with increasing in vivo implantation time. The strong affinity of BCP to TGF-β1 might provide important information for exploring the mechanism of the osteoinduction of calcium phosphates.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Acta Biomaterialia - Volume 5, Issue 4, May 2009, Pages 1311–1318
نویسندگان
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