کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1537228 996582 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Direct laser light enhancement of susceptibility of bacteria to gentamicin antibiotic
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد مواد الکترونیکی، نوری و مغناطیسی
پیش نمایش صفحه اول مقاله
Direct laser light enhancement of susceptibility of bacteria to gentamicin antibiotic
چکیده انگلیسی

ObjectivesTo test the effect of pulsed (Q-switched) and continuous wave (CW) laser light at wavelength of 532 nm on the viability of free-living stationary phase bacteria with and without gentamicin (an antibiotic) treatment.MethodsFree living stationary phase gram negative bacteria (Pseudomonas aeruginosa strain PAO1) was immersed in Luria Broth (LB) solution and exposed to Q-switched and CW lasers with and without the addition of the antibiotic gentamicin. Cell viability was determined at different time points.ResultsLaser treatment alone did not reduce cell viability compared to untreated control and the gentamicin treatment alone only resulted in a 0.5 log reduction in the viable count for P. aeruginosa. The combined laser and gentamicin treatment, however, resulted in a synergistic effect and viability was reduced by 8 logs for P. aeruginosa PAO1.ConclusionsCombination of laser light with gentamicin shows an improved efficacy against P. aeruginosa.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Optics Communications - Volume 284, Issue 23, 1 November 2011, Pages 5501–5507
نویسندگان
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