کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1548174 | 997724 | 2014 | 10 صفحه PDF | دانلود رایگان |
Hydroxyapatite (HA) co-doped with Zn2+ and F− ions was synthesized by precipitation method for the first time in this study. FTIR spectroscopy revealed Zn2+ and F− ions incorporation into HA structure. Co-doping of Zn2+ and F− ions decreased unit cell volume of HA and decreased grain sizes. Zn2+ or 5 mol% F− addition into HA significantly improved its density. Microhardness was increased with Zn2+ addition and further increase was detected with F− co-doping. Zn2+ and F− co-doped samples had higher fracture toughness than pure HA. Zn2+ incorporation to the structure resulted in an increase in cell proliferation and ALP activity of cells, and further increase was observed with 1 mol% F− addition. With superior mechanical properties and biological response 2Zn1F is a good candidate for biomedical applications.
Journal: Progress in Natural Science: Materials International - Volume 24, Issue 4, August 2014, Pages 340–349