Ultrastructural alterations in the ventricular myocardium of the adult italian newt (Lissotriton italicus) following exposure to nonylphenol ethoxylate

► Amphibians as a model to study endocrine disruptors. ► We examine the effects of nonylphenol ethoxylate upon amphibian ventricular myocardium. ► NPE treatment causes ultrastructural alterations in cardiac mitochondria and rough endoplasmic reticulum. ► NPE may induce destabilization of pospholipids interaction within membranes.