Bi2O2CO3 nanoplates: Fabrication and characterization of highly sensitive and selective cholesterol biosensor

This paper reports the development of a highly sensitive and selective amperometric cholesterol biosensor based on the bismuth subcarbonate (Bi2O2CO3) nanoplates synthesized by the facile hydrothermal process at low temperature. The detail characterization of as-synthesized material in terms of their morphological, structural and compositional properties revealed that the nanoplates are synthesized in large quantity with well-crystallinity. The fabricated biosensors exhibit a very high and reproducible sensitivity of 139.5 μAmM−1cm−2, wide linear range from 0.05 mM to 7.4 mM, fast response time of∼4s and low detection limit of 10 μM (S/N=3) for cholesterol sensing. The anti-interference ability, reproducibility, and long-term stability were also assessed. To the best of our knowledge; this is the first report which demonstrates the use of Bi2O2CO3 nanostructures for the fabrication of highly sensitive and selective cholesterol biosensor.