Conductive PANI patterns on electrospun PCL/gelatin scaffolds modified with bioactive particles for bone tissue engineering

• Bilayer electroconductive hybrid scaffolds for bone tissue engineering were produced by electrospinning and inkjet printing method.
• The addition of nanoparticles enhanced the bioactivity of scaffold.
• Presence of PANI provided electroconductivity and did not affect morphology and proliferation of cells.

In this article a method of inkjet printing applied to create conductive patterns on electrospun composite scaffolds for bone tissue engineering is presented. By incorporation of conductive polyaniline and bioactive particles and drugs (osteogenon, calcium phosphate nanoparticles) within an electrospun polycaprolactone/gelatin composite scaffold, we have obtained a biocompatible, bioactive, hybrid scaffold system, which provides an electrically conductive environment.