Evaluation of bi-functionalized mesoporous silica for solid-phase extraction of twelve endocrine disrupting compounds from water

• A new bi-functionalized mesoporous silica was prepared by one-pot synthesis.
• The material was applied for the first time as stationary phase for SPE.
• Good recoveries were obtained for the determination of 12 EDCs in waters by HPLC.

Mesoporous silica, bi-functionalized with octadecyl and aminopropyl groups was prepared and characterized. The adsorption capacity of the prepared silica for a mixture of twelve endocrine disrupting compounds in water was evaluated by solid-phase extraction and compared with a commercial phase. Analytes were determined by high performance liquid chromatography. Under optimized conditions, the material showed recoveries near 100% with standard deviations between 3 and 10%, with exception of estriol and prednisolone which showed recoveries of 66 and 82%, respectively.