کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1645395 | 1517292 | 2013 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Facile synthesis of metallized nanocontainers for the entrapment and controlled release of hydrophobic compounds Facile synthesis of metallized nanocontainers for the entrapment and controlled release of hydrophobic compounds](/preview/png/1645395.png)
Template assisted synthesis of metallized nanocontainers (MNCs) is reported by in situ synthesis of gold nanoparticles (GNPs) in the bilayer of soft lecithin micelles using aminoantipyrene as a weak reducing agent. The exact bilayer mimicry of MNCs was confirmed by electron microscopic (SEM and TEM) characterization. These MNCs were further coated with thiolated polyethylene glycol (PEG-SH) to improve their stability in aqueous media. The solubility of MNCs in polar and non-polar solvents can be tuned simply by varying their pH values. These MNCs were then used for the entrapment and controlled release of a model hydrophobic compound, pyrene, to demonstrate their potential applications for the controlled release of hydrophobic drugs.
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► Template assisted gold nanocontainers were synthesized in solution.
► UV–vis absorbance scan showed the surface plasmon resonance band at 671 nm.
► Metallized gold containers were completely water dispersible but found to have hydrophobic pockets to accommodate hydrophobic molecules.
Journal: Materials Letters - Volume 95, 15 March 2013, Pages 78–81