The effect of surface roughness and wettability of nanostructured TiO2 film on TCA-8113 epithelial-like cells

The Tca-8113 epithelia-like cells were cultured on TiO2 film deposited on glass by dc reactive magnetron sputtering. Surface properties of the TiO2 film including surface roughness and wettability were characterized and discussed in dependence on sputtering power. XRD showed that the deposited films were amorphous. Cell behaviors including adhesion, spreading and proliferation on the TiO2 film were observed and analyzed as a function of the surface property of TiO2 film. The study provides a potential application of reactive plasma technology to improve the cytocompatibility of Ti/Ti6Al4V as dental and orthopedic implants, since it is possible to design and optimize the nanostructure of the deposited film for better bio-function by adjusting process parameters in deposition.