Facile and environmentally friendly halogenation of BODIPYs in deep eutectic solvent

• A deep eutectic solvent ChCl/HFIP was prepared from choline chloride and hexafluoroisopropanol.
• A rapid and environmentally friendly halogenation of BODIPYs in the deep eutectic solvent was achieved.
• The deep eutectic solvent could be readily recovered and reused for several runs.

A deep eutectic solvent based on choline chloride and 1,1,1,3,3,3-hexafluoro-2-propanol was prepared. This deep eutectic solvent was used as the reaction medium for halogenation of boron dipyrromethene in the presence of N-halosuccinimide, which delivered the corresponding products in good to excellent yields (79–94%) in short reaction time (usually within 30 min). Moreover, this deep eutectic solvent could be easily prepared, recovered and reused for several runs without significant loss in the yields.

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