Keywords: 1,4-Addition; Hexafluoroisopropanol; Trifluoroethanol; Aromatic amines;
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Keywords: AcOH; acetic acid; ACN; acetonitrile; APCI; atmospheric pressure chemical ionization; BSTFA; N,O-bis(trimethylsilyl)trifluoroacetamide; CBCA; cannabichromenic acid; CBC; cannabichromene; CBDA; cannabidiolic acid; CBD; cannabidiol; CBDVA; cannabidivarinic
Recent developments in enantioselective lanthanide-catalyzed transformations
Keywords: Ar; aryl; BINOL; 1,1â²-bi-2-naphthol; Bpy; 2,2â²-bipyridyl; Bn; benzyl; BNP; Binaphthophosphole; Boc; tert-butoxycarbonyl; BSA; bis-(trimethylsilyl)acetamide; CB; carbon black; cod; 1,5-cyclooctadiene; Cy; cyclohexyl; DBDMH; 1,3-dibromo-5,5-dimethylhyda
Keywords: Polyglutamine; Huntington's disease; Disaggregation; Solubilization; Trifluoroacetic acid; Hexafluoroisopropanol; polyGln; polyglutamine; DMSO; dimethyl sulfoxide; TFA; trifluoroacetic acid; HFIP; hexafluoroisopropanol; ThT; thioflavin T; PBS; phosphate-b
Keywords: Sulfatase; Enzyme; Inhibitor; Estrogen; Cancer; SERM; ALP; alkaline phosphatase; DEA; diethylamine; DHEA; dehydroepiandrosterone; DHEAS; dehydroepiandrosterone sulfate; 5-diol; 5-androstene-3β,17β-diol; DIPEA; diisopropylamine; E1; estrone; E1S; estrone
Keywords: Ac; acetyl; acac; acetylacetonate; AHPCS; allylhydridopolycarbosilane; Bn; benzyl; Boc; tert-butoxycarbonyl; BPR; back pressure regulator; bpy; 2,2â²-bipyridine; Bu; butyl; CFL; compact fluorescent lamp; DCB; 1,4-dicyanobenzene; de; diastereomeric excess
Keywords: Hexafluoroisopropanol; Vesicle; Cetyltrimethylammonium bromide; Sodium dodecyl sulfate; Pseudostationary phase; Electrokinetic chromatography;
Keywords: Deep eutectic mixture; Hexafluoroisopropanol; Aryl/heteroaryl boronic acids; Phenols
Hexafluoroisopropanol-based hydrophobic deep eutectic solvents for dispersive liquid-liquid microextraction of pyrethroids in tea beverages and fruit juices
Keywords: Deep eutectic solvent; Hexafluoroisopropanol; Dispersive liquid-liquid microextraction; Pyrethroids; Tea beverages; Fruit juices; Transfluthrin (PubChem CID: 656612); Fenpropathrin (PubChem CID: 47326); Fenvalerate (PubChem CID: 3347); Ethofenprox (PubChe
Hexafluoroisopropanol-induced salt-free catanionic surfactant coacervate extraction method for determination of fluoroquinolones in milk samples
Keywords: Salt-free catanionic surfactant; Hexafluoroisopropanol; Coacervate extraction; Fluoroquinolone; Milk;
Screening for amyloid-β aggregation inhibitor and neuronal toxicity of eight Tunisian medicinal plants
Keywords: Aβ42; β-Amyloid peptide 42; ABTS; 2â²-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid; AD; Alzheimer disease; BSA; bovine serum albumin; CD; Circular Dichroism; CM-H2 DCFDA; 2,7-dichlorofluorescin diacetate acetyl ester; CTX-B; cholera toxin subunit
Rationally designed divalent caffeic amides inhibit amyloid-β fibrillization, induce fibril dissociation, and ameliorate cytotoxicity
Keywords: Amyloid-β; Alzheimer's disease; Caffeic acid; Divalent caffeic amide; Inhibitor; Cytotoxicity; Aβ; amyloid-β; AD; Alzheimer's disease; CA; caffeic acid; CCS; collision cross-section; DMF; dimethylformamide; EDCI; 1-ethyl-3-(3-dimethylaminopropyl) carbo
Evolution of clinical and environmental health applications of exhaled breath research: Review of methods and instrumentation for gas-phase, condensate, and aerosols
Keywords: Breath research; Exhaled breath condensate (EBC); Exhaled breath aerosol (EBA); Volatile organic compounds (VOCs); Analytical techniques; Biomarkers; 1D; one-dimensional; ADME; absorption, distribution, metabolism, and excretion; AOP; adverse outcome path
From nano to micro to macro: Electrospun hierarchically structured polymeric fibers for biomedical applications
Keywords: 0-D; zero dimensional; 1-D; one dimensional; 2-D; two dimensional; 3-D; three dimensional; anti-EpCAM; anti-epithelial cell adhesion molecule; bFGF; basic fibroblast growth factor; BSHFs; bead-on-string heterostructured fibers; CFU; Colony-Forming Units;
A highly sensitive method for the simultaneous UHPLC-MS/MS analysis of clonidine, morphine, midazolam and their metabolites in blood plasma using HFIP as the eluent additive
Keywords: UHPLC-MS/MS; Chromatographic separation; Morphine; Clonidine; Midazolam; Hexafluoroisopropanol;
Fischer carbene mediated covalent grafting of a peptide nucleic acid on gold surfaces and IR optical detection of DNA hybridization with a transition metalcarbonyl label
Keywords: AFM; atomic force microscopy; DIPEA; diisopropylethylamine; HFIP; hexafluoroisopropanol; MBHA; 4-methylbenzylhydrylamine; MUA; 11-mercaptoundecanoic acid; NS; nanoshaving; PNA; peptide nucleic acid; ODN; oligonucleotide; PBS; phosphate buffered saline; PM
Research reportAmyloid-β42 protofibrils are internalized by microglia more extensively than monomers
Keywords: AD; Alzheimer's disease; Aβ; amyloid-β protein; aCSF; artificial cerebrospinal fluid; HFIP; hexafluoroisopropanol; PBS; phosphate-buffered saline; SEC; size exclusion chromatography; TEM; transmission electron microscopy; TNFα; tumor necrosis factor α
Aβ40 has a subtle effect on Aβ42 protofibril formation, but to a lesser degree than Aβ42 concentration, in Aβ42/Aβ40 mixtures
Keywords: Amyloid-beta protein; Aggregation; Protofibrils; Light scattering; AD; Alzheimer's disease; Aβ; amyloid-β protein; aCSF; artificial cerebrospinal fluid; DLS; dynamic light scattering; HFIP; hexafluoroisopropanol; RH; hydrodynamic radius; Rg; root mean s
Oxidative stress and mitochondria-mediated cell death mechanisms triggered by the familial Danish dementia ADan amyloid
Keywords: Aβ; amyloid-β; AD; Alzheimer's disease; ANS; 8-anilinonapthalene-1-sulfonic acid; CAA; cerebral amyloid angiopathy; CAPS; 3-cyclohexamino-1-propanesulfonic acid; CD; circular dichroism; CNS; central nervous system; cyt c; cytochrome c; DCFDA; 2â²,7â²-
Facile and environmentally friendly halogenation of BODIPYs in deep eutectic solvent
Keywords: Deep eutectic solvent; Hexafluoroisopropanol; Halogenation; Boron dipyrromethene; Green chemistry; Fluorescent dye
Simultaneous separation of acidic and basic proteins using gemini pyrrolidinium surfactants and hexafluoroisopropanol as dynamic coating additives in capillary electrophoresis
Keywords: Capillary electrophoresis; Dynamic coating; Pyrrolidinium gemini surfactant; Hexafluoroisopropanol; Protein separation;
New examples of template catalysis based processes: glycerol-like units as efficient promoters for dehydrative nucleophilic substitutions of ferrocenylmethanol
Keywords: Template catalysis; Glycerol; Ferrocenylmethyl ethers; Hydrogen bonding; Hexafluoroisopropanol; Antifungal activity;
CD47 does not mediate amyloid-β(1-42) protofibril-stimulated microglial cytokine release
Keywords: AD; Alzheimer's disease; Aβ; amyloid-β protein; aCSF; artificial cerebrospinal fluid; HFIP; hexafluoroisopropanol; IL-1β; interleukin-1β; SEC; size exclusion chromatography; ThT; thioflavin T; TNFα; tumor necrosis factor α; Amyloid-beta protein; A
Biomonitoring occupational sevoflurane exposure at low levels by urinary sevoflurane and hexafluoroisopropanol
Keywords: Sevoflurane; Hexafluoroisopropanol; Biomarkers; Biological monitoring; Operating room personnel;
HIV-1 Tat membrane interactions probed using X-ray and neutron scattering, CD spectroscopy and MD simulations
Keywords: (DOPC); dioleoylphosphocholine; (DOPE); dioleoylphosphoethanolamine; (DOPS); dioleoylphosphoserine; (POPC); palmitoyloleoylphosphocholine; (POPE); palmitoyloleoylphosphoethanolamine; (POPS); palmitoyloleoylphosphoserine; (Soy PI); soy phosphoinositol; (SM
Stability of early-stage amyloid-β(1-42) aggregation species
Keywords: AD; Alzheimer's disease; Aβ; amyloid-β protein; GuHCl; guanidine hydrochloride; HFIP; hexafluoroisopropanol; SDS; sodium dodecyl sulfate; SEC; size exclusion chromatography; ThT; thioflavin T; Amyloid-beta protein; Aggregation; Fibrillar oligomer;
Proanthocyanidins are the major anti-diabetic components of cinnamon water extract
Keywords: CD; circular dichroism; CWE; cinnamon water extract; EGCG; (â)-epigallocatechin 3-gallate; HFIP; hexafluoroisopropanol; hIAPP; human islet amyloid polypeptide; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PA; proanthocyanidins; PBS
A simple, efficient and green procedure for the synthesis of bis-indolyl methanes in 1,1,1,3,3,3-hexafluoro-2-propanol
Keywords: Hexafluoroisopropanol; Recyclable; Indole; Bis-indolyl methane
Determination of sevoflurane and its metabolite hexafluoroisopropanol by direct injection of human plasma into gas chromatography–tandem mass spectrometry
Keywords: Direct injection; Plasma; GC–MS/MS; Anesthetics; Sevoflurane; Hexafluoroisopropanol
Silibinin inhibits the toxic aggregation of human islet amyloid polypeptide
Keywords: CD; circular dichroism; EGCG; (â)-epigallocatechin 3-gallate; HFIP; hexafluoroisopropanol; hIAPP; human islet amyloid polypeptide; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; T2DM; type 2 diabetes mellitus; TEM; transmission elect
Unusual photobehavior of benzophenone triplets in hexafluoroisopropanol. Inversion of the triplet character of benzophenone
Keywords: Benzophenone; Hexafluoroisopropanol; Hydrogen-bonding; Triplet inversion; Electron transfer
Inhibitory effect of curcumin on the Al(III)-induced Aβ42 aggregation and neurotoxicity in vitro
Keywords: AD; Alzheimer's disease; Aβ42; amyloid-β 42; Al(III); Aluminum ion; CD; circular dichroism; ThT; thioflavin T; AFM; atomic force microscopy; HFIP; hexafluoroisopropanol; CBB; Coomassie Brilliant Blue; A595; absorption at wavelength of 595 nm; Alzheimer
Crocetin inhibits beta-amyloid fibrillization and stabilizes beta-amyloid oligomers
Keywords: Aβ; beta-amyloid; AD; Alzheimer's disease; HSA; human serum albumin; BBB; blood-brain barrier; HPLC; high-performance liquid chromatography; MALDI-TOF; matrix-assisted laser desorption/ionization time-of-flight mass spectrometry; HFIP; hexafluoroisop
Fluoroalcohols as novel buffer components for basic buffer solutions for liquid chromatography electrospray ionization mass spectrometry: Retention mechanisms
Keywords: Buffer additive; Hexafluoroisopropanol; Hexafluoro-tert-buthanol; Electrospray (ESI); Retention mechanisms
Porcine islet amyloid polypeptide fragments are refractory to amyloid formation
Keywords: CD; circular dichroism; HFIP; hexafluoroisopropanol; IAPP; islet amyloid polypeptide; MTT; 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; SEC; size-exclusion chromatography; SPPS; solid phase peptide synthesis; T2DM; type 2 diabetes mellitu
L-selectin transmembrane and cytoplasmic domains are monomeric in membranes
Keywords: CAT; chloramphenicol acetyl transferase; CD; circular dichroism; DPC; dodecylphosphocholine; FRET; fluorescence resonance energy transfer; GST; glutathione S-transferase; HFIP; hexafluoroisopropanol; HPLC; high performance liquid chromatography; PSGL-1; P
Lewis acid catalyst free synthesis of benzimidazoles and formamidines in 1,1,1,3,3,3-hexafluoro-2-propanol
Keywords: Benzimidazole; Formamidine; Hexafluoroisopropanol; Hydrogen bonding
Elaboration of a Lewis acid-free protocol for the alkylation of silicon-containing Ï-donors by β-arylthioalkyl chlorides
Keywords: Electrophilic addition; Trifluoroethanol; Hexafluoroisopropanol; Hydrogen bonds;
Monitoring the effects of strong cosolvent hexafluoroisopropanol in investigation of the tetrameric structure and stability of K+-channel KcsA
Keywords: Potassium channel KcsA; Tetrameric stability; Hexafluoroisopropanol; Tryptophan fluorescence; Circular dichroism; Membrane lateral pressure; Protein–lipid interaction
Separation of fluorinated amino acids and oligopeptides from their non-fluorinated counterparts using high-performance liquid chromatography
Keywords: Cys; cysteine; DCM; dichloromethane; DIC; N,Nâ²-diisopropylcarbodiimide; DIPEA; N,N-diisopropylethylamine; DMF; N,N-dimethylformamide; EtOH; ethanol; F%wt; fluorine weight percentage in an analyte or a solvent; Fmoc; fluorenylmethoxycarbonyl; HFIP; hexaf
Selectivity patterns in micellar electrokinetic chromatography
Keywords: MEKC; Electrokinetic chromatography; Micellar selectivity triangle; Selectivity classification; Alcohol-modified micelles; Fluorinated alcohols; Hexafluoroisopropanol; SDS; TTAB; LiPFOS; Solvation parameters;
Dunaliella salina extract effect on diabetic rats: Metabolic fingerprinting and target metabolite analysis
Keywords: ANOVA; analysis of variance; BGE; background electrolyte; CE; capillary electrophoresis; EDTA; ethylene diamino tetra acetic; GSH; reduced glutathione; GSSG; oxidized glutathione; HFIP; hexafluoroisopropanol; LV; latent variable; PCA; principal component
Facile and efficient synthesis of 2-substituted-N1-carbethoxy-2,3-dihydro-4(1H)-quinazolinones in fluorous solvent
Keywords: Quinazolinones; Trifluoroethanol; Hexafluoroisopropanol; Fluorous solvent; Solvent effect
Molecular and electronic structures, infrared spectra, and vibrational assignment for ap and sc conformers of hexafluoro-iso-propanol
Keywords: Hexafluoroisopropanol; Hyperconjugation; Infrared spectra; Vibrational assignment; DFT calculations
Potential pathogenic role of β-amyloid1-42-aluminum complex in Alzheimer's disease
Keywords: AD; Alzheimer's disease; Aβ; β-amyloid; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; DPH; 1,6-diphenyl-1,3,5-hexatriene; TMA-DPH; N,N,N-trimethyl-4-(6-phenyl-1,3,5-hexatrien-1-yl) phenylammonium p-toluenesulfonate; ETASS; electroth
Synthesis and evaluation of anilinohexafluoroisopropanols as activators/modulators of LXRα and β
Keywords: Hexafluoroisopropanol; Aniline; Liver-X-receptor activators/modulators; SAR; Molecular modeling
Solid-phase synthesis of backbone-cyclized β-helical peptides
Keywords: Alkanesulfonamide; Safety-catch linker; Cyclic peptide; Solid-phase peptide synthesis; β-Hairpin; β-Turn; β-Helix; HPLC; Gel-permeation chromatography; AS-SLC; alkanesulfonamide safety-catch linker; CBC; cleavage-by-cyclization; Boc; t-butoxycarbonyl;
Simultaneous determination of unmodified sevoflurane and of its metabolite hexafluoroisopropanol in urine by headspace sorptive extraction-thermal desorption-capillary gas chromatography-mass spectrometry
Keywords: Sevoflurane; Hexafluoroisopropanol; Biomarkers of exposure; Urine; Biological monitoring; Headspace sorptive extraction; Capillary GC-MS;
Effect of detergents and hexafluoroisopropanol on the conformation of a non-helical and a helical plant protease inhibitor
Keywords: Plant protease inhibitor; Detergents; Hexafluoroisopropanol; Circular dichroism;
Separation and quantification of a novel two-component vaccine adjuvant
Keywords: AUC; area under the curve; HFIP; hexafluoroisopropanol; IC31; two-component adjuvant comprising KLK and ODN1a; IEX; ion exchange; IU; international units; KLK; 11-mer cationic peptide; component of IC31; MALDI-TOF; matrix-assisted laser desorption ionisat