Separation of fluorinated amino acids and oligopeptides from their non-fluorinated counterparts using high-performance liquid chromatography

Chromatographic separation of fluorinated amino acids and oligopeptides from their non-fluorinated counterparts were investigated at various temperatures using both hydrocarbon and fluorocarbon eluents and columns. The results show that fluorinated amino acids and oligopeptides demonstrate preference toward fluorocarbon eluents and fluorocarbon column compared to their non-fluorinated counterparts.