Keywords: 1,4-Addition; Hexafluoroisopropanol; Trifluoroethanol; Aromatic amines;
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Keywords: HER; hydrogen evolution reaction; OER; oxygen evolution reaction; ORR; oxygen reduction reaction; CO2RR; carbon dioxide reduction; EOR; alcohol oxidation reaction; CV; cyclic voltammetry; LSV; linear sweep voltammetry; CPE; constant potential electrolysis
Keywords: Aggregates; Partially folded state; Hydrophobic clusters; Molten globule; Secondary structure; Glyoxal; Trifluoroethanol;
Keywords: AMA; amantadine; BFM; bond fluctuation method; BST-2; bone marrow stromal cell antigen 2; CD; circular dichroism; CGMD; coarse-grained molecular dynamics; ClyA; cytolysin A; DHPC; dihexanoylphosphocholine; DPC; dodecylphosphocholine; E. coli; Escherichia
Keywords: Aggregates; Fibrinogen; Fibrillar; Prefibrillar; Trifluoroethanol;
Keywords: AMPs; antimicrobial peptides; SmAE; S. s. mutilans Assembled EST; ATCC; American Type Culture Collection; KCTC; Korean Collection for Type Cultures; MIC; minimum inhibitory concentration; PBS; phosphate-buffered saline; CD; circular dichroism; TFE; triflu
Keywords: BCS; biopharmaceutics classification system; bFGF; basic fibroblast growth factor; BMC; bone morphogenetic protein; CA; cellulose acetate; CD; cyclodextrin; CS; chitosan; CS-EDTA; chitosan-ethylenediaminetetraacetic acid; CR; controlled release; DMAc;
Keywords: ALS; amyotrophic lateral sclerosis; DM; degenerative myelopathy; GWAS; genome-wide association study; IPTG; isopropyl-β-d-1-thiogalactopyranoside; SOD1; superoxide dismutase 1; TFE; trifluoroethanol;
Microcystins: Synthesis and structure-activity relationship studies toward PP1 and PP2A
Keywords: Adda; (2S,3S,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid; Amba; (2S,3S)-3-amino-2-methylbutanoic acid; Boc; tert-butoxycarbonyl; BOP; benzotriazol-1-yloxy-tris-dimethylaminophosphoniumhexafluoro phosphate; Cbz; carboxybenzyl; D
Novel bioactive peptides from PD-L1/2, a type 1 ribosome inactivating protein from Phytolacca dioica L. Evaluation of their antimicrobial properties and anti-biofilm activities
Keywords: CD; circular dichroism; CNBr; cyanogen bromide; LPS; lipopolysaccharide; Na/P; sodium phosphate buffer; SDS; sodium dodecyl sulphate; TFE; trifluoroethanol; Trisâ¢Cl; Tris(hydroxymethyl)aminomethane-HCl buffer; SEM; standard error of the mean; LAL; Limul
Probing the effect of membrane contents on transmembrane protein-protein interaction using solution NMR and computer simulations
Keywords: TM; transmembrane; ErbB4tm; transmembrane domain of human ErbB4 receptor; DLPC; 1,2-dilauroyl-sn-glycero-3-phosphocholine; DMPC; 1,2-dimyristoyl-sn-glycero-3-phosphocholine; POPC; 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine; DPPC; 1,2-dipalmitoyl-sn-
From nano to micro to macro: Electrospun hierarchically structured polymeric fibers for biomedical applications
Keywords: 0-D; zero dimensional; 1-D; one dimensional; 2-D; two dimensional; 3-D; three dimensional; anti-EpCAM; anti-epithelial cell adhesion molecule; bFGF; basic fibroblast growth factor; BSHFs; bead-on-string heterostructured fibers; CFU; Colony-Forming Units;
Structural insights into the interaction of a monoclonal antibody and Nodal peptides by STD-NMR spectroscopy
Keywords: ActRIIA; activin type II receptor A; ActRIIB; activin type II receptor B; ALK; activin receptor-like kinase; CFC; Cripto-1/FLR1/cryptic; ECD; extracellular domain; EGF; epidermal growth factor; GEM; Group epitope mapping; mAb; monoclonal antibody; SMAD; S
Apela exhibits isoform- and headgroup-dependent modulation of micelle binding, peptide conformation and dynamics
Keywords: AR; apelin receptor (APJ); CCSD; combined chemical shift displacement; CD; circular dichroism; CSI; chemical shift index; DANGLE; Dihedral Angles from Global Likelihood Estimates; DOSY; diffusion ordered spectroscopy; DPC; dodecylphosphocholine; DSS; 2,2-
Electrospray Synthesis of Poly(lactide-co-glycolide) Nanoparticles Encapsulating Peptides to Enhance Proliferation of Antigen-Specific CD8+ T Cells
Keywords: electrospray; PLGA; peptide encapsulation; vaccine; controlled drug delivery; NP; nanoparticles; PLGA; poly(lactide-co-glycolide); CMV; cytomegalovirus; PBMCs; peripheral blood mononuclear cells; W/O/W; water-in-oil-in-water; PVA; polyvinylalcohol; DMSO;
PGLa-H tandem-repeat peptides active against multidrug resistant clinical bacterial isolates
Keywords: AO; Acridine orange; EtBr; ethidium bromide; DLPC; 1,2-dilauroyl-sn-glycero-3-phosphocholine, diC12; DMSO; dimethyl sulphoxide; dPG; diphosphatidylglycerol; EDTA; ethylenediaminetetraacetic acid; ESBL; extended-spectrum β-lactamase; FBS; foetal bovine se
Folding thermodynamics of c-Myb DNA-binding domain in correlation with its α-helical contents
Keywords: CD; circular dichroism; DSC; differential scanning calorimetry; TFE; trifluoroethanol; Tm; transition temperature; Td; denaturation temperature; ÎCp; heat capacity change; ÎG; Gibbs free energy change; ÎHcal; calorimetric enthalpy change; ÎH; enthalpy
Dimerization interface and dynamic properties of yeast IF1 revealed by Site-Directed Spin Labeling EPR spectroscopy
Keywords: CD; Circular Dichroism; cw; continuous wave; DEER; Double Electron-Electron Resonance; DTT; dithiothreitol; EPR; Electron Paramagnetic Resonance; IF1; endogenous inhibitory peptide of mitochondrial ATP synthase; bIF1; IF1 from bovine; yIF1; IF1 from yea
Antimicrobial and host cell-directed activities of Gly/Ser-rich peptides from salmonid cathelicidins
Keywords: Antimicrobial peptide; Trout cathelicidin; Antibacterial activity; Immunomodulation; Head kidney leukocytes; AMP; Antimicrobial peptide; BSA; Bovine serum albumin; CD; Circular dichroism; CFU; Colony forming units; DCM; Dichloromethane; DIPEA; Diisopropyl
A new active antimicrobial peptide from PD-L4, a type 1 ribosome inactivating protein of Phytolacca dioica L.: A new function of RIPs for plant defence?
Keywords: CD; circular dichroism; CNBr; cyanogen bromide; LPS; lipopolysaccharide; Na/P; sodium phosphate buffer; TFE; trifluoroethanol; Tris·Cl; Tris(hydroxymethyl)aminomethane-HCl buffer; Antimicrobial peptide; Cationic antimicrobial peptide; Ribosome inactiva
Pyridoxamine protects proteins from damage by hypohalous acids in vitro and in vivo
Keywords: CID; collision-induced dissociation; ECM; extracellular matrix; GdnCl; guanidinium hydrochloride; LC-MS/MS; liquid chromatography coupled with tandem mass spectrometry; PM; pyridoxamine; TFE; trifluoroethanol; Diabetes; Nephropathy; Hypochlorous acid; H
Solvent effects in gold-catalysed A3-coupling reactions
Keywords: Gold; A3-reaction; Trifluoroethanol; Microwave; Solvent effect;
A mesoporous silica/fluorinated alcohol adduct: an efficient metal-free, three-component synthesis of indazolophthalazinetrione heterocycles using a reusable nanoporous/trifluoroethanol adduct (SBA-15/TFE)
Keywords: Multicomponent reaction; Trifluoroethanol; SBA-15; Indazolophthalazinetriones;
Intermediate conformation between native β-sheet and non-native α-helix is a precursor of trifluoroethanol-induced aggregation of Human Carbonic Anhydrase-II
Keywords: Human carbonic anhydrase II; Trifluoroethanol; Protein aggregation; Amyloid fibril; Partially structured conformation;
Toll-like receptor 3 transmembrane domain is able to perform various homotypic interactions: An NMR structural study
Keywords: TM; transmembrane; DPC; dodecylphosphocholine; TMD; isolated transmembrane domain; TLR; toll-like receptor; TFE; trifluoroethanol; TIR; Toll-interleukin I receptor domain; NOE; nuclear overhauser effect; NOESY; NOE spectroscopy; ECD; extracellular domain;
In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome
Keywords: Epithelial ovarian cancer; Exosomes; Mass spectrometry; Proteomics; Trifluoroethanol;
NMR-based approach to measure the free energy of transmembrane helix-helix interactions
Keywords: NMR; nuclear magnetic resonance; DPC; dodecylphosphocholine; TM; transmembrane; TMD; transmembrane domain; LPR; lipid to protein ratio; CMC; critical micelle concentration; FRET; Forster resonance energy transfer; FGFR3; fibroblast growth factor receptor
Toward a common aggregation mechanism for a β-barrel protein family: Insights derived from a stable dimeric species
Keywords: IFABP; intestinal fatty acid binding protein; Î98Î; a truncated variant of IFABP corresponding to the fragment 29-126 of the parent protein; Î78Î; a truncated variant of IFABP corresponding to the fragment 29-106 of the parent protein; TFE; 2,2,2-
HIV-1 Tat membrane interactions probed using X-ray and neutron scattering, CD spectroscopy and MD simulations
Keywords: (DOPC); dioleoylphosphocholine; (DOPE); dioleoylphosphoethanolamine; (DOPS); dioleoylphosphoserine; (POPC); palmitoyloleoylphosphocholine; (POPE); palmitoyloleoylphosphoethanolamine; (POPS); palmitoyloleoylphosphoserine; (Soy PI); soy phosphoinositol; (SM
Conformational behaviour and aggregation of chickpea cystatin in trifluoroethanol: Effects of epicatechin and tannic acid
Keywords: Chick pea cystatin; Tannic acid; Trifluoroethanol; Secondary structure; Aggregation; Polyphenols
2,2,2-Trifluoroethanol disrupts the triple helical structure and self-association of type I collagen
Keywords: Circular dichroism; Collagen; Peptide; Trifluoroethanol; Unordered;
PPIase independent chaperone-like function of recombinant human Cyclophilin A during arginine kinase refolding
Keywords: ANS; 8-anilino-1-naphthalenesulfonate; CyPA and rhCyPA; cyclophilin A and recombinant human cyclophilin A; CsA; cyclosporin A; PPIase; peptidyl-prolyl cis-trans isomerase; SDS-PAGE; sodium dodecyl sulfate-polyacrylmide gel electrophoresis; Suc-AAP
Purification and biochemical characterization of angiotensin I-converting enzyme (ACE) from ostrich lung: The effect of 2,2,2-trifluoroethanol on ACE conformation and activity
Keywords: Angiotensin I-converting enzyme; Ostrich lung; Chromatography; Detergent; Trifluoroethanol;
Selective antimicrobial activity and mode of action of adepantins, glycine-rich peptide antibiotics based on anuran antimicrobial peptide sequences
Keywords: AMP; antimicrobial peptide; BODIPY; boron-dipyrromethene; Gal-ONp; o-nitrophenyl-β-D-galactopyranoside; HC50; concentration for 50% haemolysis; IC50; concentration for 50% of growth inhibition; LUVs; large unilamellar vesicles; MIC; minimum inhibitory co
The helical propensity of KLA amphipathic peptides enhances their binding to gel-state lipid membranes
Keywords: FDA; Food and Drug Administration; TFE; Trifluoroethanol; ITC; Isothermal titration calorimetry; DLS; Dynamic light scattering; DSC; Differential scanning calorimetry; CD; Circular dichroism spectroscopy; LUVs; Large unilamellar vesicles; SUVs; Small unil
Zinc-binding and structural properties of the histidine-rich loop of Arabidopsis thaliana vacuolar membrane zinc transporter MTP1
Keywords: Circular dichroism spectroscopy; Histidine-rich loop; Isothermal titration calorimetry; Metal tolerance protein; Zinc binding; Zinc transporter; CTD; carboxyl terminal domain; His-loop; histidine-rich loop; ITC; isothermal titration calorimetry; MTP; meta
Triflic acid catalyzed isobutane alkylation with trifluoroethanol as a promoter
Keywords: Alkylation; Isobutane; Butene; Triflic acid; Trifluoroethanol
A facile and efficient synthesis of 2,2,2-trifluoroethyl 2-[(E)-N-phenylcinnamamido]-2-phenylacetates in trifluoroethanol via sequential Ugi four-component reaction/esterification
Keywords: Ugi-4CR; Trifluoroethanol; Sequential Ugi-4CR/trifluoroethyl esterification;
Solution NMR analysis of the binding mechanism of DIVS6 model peptides of voltage-gated sodium channels and the lipid soluble alkaloid veratridine
Keywords: CD; circular dichroism; DQF-COSY; double-quantum filtered-correlation spectroscopy; MALDI-TOF MS; matrix-assisted laser desorption/ionization time-of-flight mass spectrometry; NOESY; nuclear overhauser enhancement and exchange spectroscopy; TFE; trifluoro
Towards alpha-glucosidase folding induced by trifluoroethanol: Kinetics and computational prediction
Keywords: pNPG; p-nitrophenyl α-d-glucopyranoside; pNP; 4-nitrophenol; ANS; 1-anilino-8-naphthalenesulfonate; TFE; 2,2,2-trifluoroethanol; Alpha-glucosidase; Trifluoroethanol; Unfolding; Docking simulation; Molecular dynamics;
Trifluoroethanol and acetonitrile induced formation of the molten globule states and aggregates of cellulase
Keywords: Acetonitrile; Aggregates; Cellulase; Molten globule states; Trifluoroethanol
Functional and conformational changes in the aspartic protease cardosin A induced by TFE
Keywords: Aspartic proteases; Trifluoroethanol; Circular dichroism; Calorimetry; Molecular dynamics simulations;
Orientation and depth of surfactant protein B C-terminal helix in lung surfactant bilayers
Keywords: RDS; Respiratory Distress Syndrome; ARDS; Acute Respiratory Distress Syndrome; SP-B; Surfactant Protein B; SDS; sodium dodecyl sulfate; BLES; bovine lipid extract surfactant; MD; molecular dynamics; Fmoc; O-fluorenylmethyl-oxycarbonyl; r.h.; relative humi
Interaction with membranes of the full C-terminal domain of protein NS4B from Hepatitis C virus
Keywords: 5-NS; 5-doxyl-stearic acid; 16-NS; 16-doxyl-stearic acid; 14BMP; bis(monomyristoylglycero)phosphate; 18BMP; bis(monooleoylglycero)phosphate; BPI; bovine brain l-α-phosphatidylinositol; BPS; bovine brain l-α-phosphatidylserine; CF; 5-carboxyfluorescein;
The disordered C-terminus of the RNA Polymerase II phosphatase FCP1 is partially helical in the unbound state
Keywords: CSI, chemical shift index; FCP1, transcription factor IIF associating CTD phosphatase 1; IDP, intrinsically disordered protein; TFE, 2,2,2-trifluoroethanolFCP1; Intrinsically disordered protein; RNA polymerase; NMR; Circular dichroism; Trifluoroethanol
Porcine islet amyloid polypeptide fragments are refractory to amyloid formation
Keywords: CD; circular dichroism; HFIP; hexafluoroisopropanol; IAPP; islet amyloid polypeptide; MTT; 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; SEC; size-exclusion chromatography; SPPS; solid phase peptide synthesis; T2DM; type 2 diabetes mellitu
False EX1 signatures caused by sample carryover during HX MS analyses
Keywords: IPA; isopropanol; ACN; acetonitrile; MeOH; methanol; FA; formic acid; TFE; trifluoroethanol; TFA; trifluoroacetic acid; DMSO; dimethyl sulfoxide; HX MS; hydrogen exchange mass spectrometry; Peptide carryover; EX1 kinetics; Hydrogen exchange; Mass spectrom
Trifluoroethanol-induced conformational changes in α- and β-neoendorphins monitored using hydrogen/deuterium exchange mass spectrometry and circular dichroism spectroscopy
Keywords: ACTH; adrenocorticotropic hormone; CD; circular dichroism; CID; collision-induced dissociation; ESI; electrospray ionization; FT-IR; Fourier-transform-infrared; HX; hydrogen/deuterium exchange; MS/MS; tandem mass spectrometry; NE; neoendorphin; NMR; nucle
Assays for α-synuclein aggregation
Keywords: cac; critical aggregation concentration; scc; super-critical concentration; Amyloid; Plate reader assay; Thioflavin T; Shared micelles; SDS; Trifluoroethanol; Natively disordered proteins; Alpha-synuclein;
Phospholipid membrane-interaction of a peptide from S4 segment of KvAP K+ channel and the influence of the positive charges and an identified heptad repeat in its interaction with a S3 peptide
Keywords: Voltage-gated potassium channels; Voltage-sensing domain; S3 and S4 segments; Interaction of S3 and S4 peptides; Peptide-lipid interaction; Membrane-assembly of peptides; TM; transmembrane; Kv; voltage-gated potassium channel; PBS; phosphate buffer sali