کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1199330 | 1493522 | 2015 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Hexafluoroisopropanol-modified cetyltrimethylammonium bromide/sodium dodecyl sulfate vesicles as a pseudostationary phase in electrokinetic chromatography
ترجمه فارسی عنوان
هیستفلوریزوپروپانول-اصلاح شده استیلت تریمتیل آمونیوم برمید / سدیم داودسیل سولفات به عنوان فاز شبه موقت در کروماتوگرافی الکترو کینتیک
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
A novel catanionic surfactant vesicle system, formulated from hexafluoroisopropanol (HFIP), cetyltrimethylammonium bromide (CTAB) and sodium dodecyl sulfate (SDS), was developed as pseudostationary phase (PSP) in electrokinetic chromatography (EKC). HFIP, as an organic modifier with the prominent properties of ionization, hydrogen bond donor and hydrophobicity, was used to effectively promote the spontaneous vesicle formation from CTAB/SDS mixed aqueous solutions, where precipitates are easy to occur due to long carbon chains, and adjust the performance of CTAB/SDS vesicles. The physical features (size and viscosity) and electrophoretic parameters (electroosmotic mobility, electrophoretic mobility and elution range) of HFIP-modified CTAB/SDS vesicles were characterized as HFIP volume content (0-4%, v/v), CTAB/SDS molar ratio (2:8-7:3Â mol/mol) and total surfactant concentration (10-50Â mM) varying, respectively. The 3% v/v HFIP-modified CTAB/SDS (3:7Â mol/mol, 50Â mM) vesicle system proves to have the largest mean diameter (288.20Â nm) and the widest elution range (12.41), which is also much wider than that of the corresponding other four PSP systems including trifluoroethanol (TFE)-modified CTAB/SDS vesicles (5.69), isopropanol-modified CTAB/SDS micelles (2.03), HFIP-modified SDS micelles (4.86) and unmodified SDS micelles (3.12). The chromatographic performance of the HFIP-modified vesicle system was evaluated by separating eight polycyclic aromatic hydrocarbons, nitrotoluene positional isomers, five positively charged and five negatively charged/neutral drugs, respectively. Baseline or near-baseline separation was achieved for each series of solutes. Compared with the TFE-modified vesicle system, as well as the HFIP-modified and unmodified SDS micelle systems, the HFIP-modified vesicle system shows the best separation selectivity, the highest or comparable efficiency, and the lowest retention.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1404, 24 July 2015, Pages 131-140
Journal: Journal of Chromatography A - Volume 1404, 24 July 2015, Pages 131-140
نویسندگان
Yu Tian, Yunfang Li, Jie Mei, Bin Deng, Yuxiu Xiao,