Structural and functional stabilities of artificially designed DNA ultra-thin films grown by silica Assistance

We report the structural and functional stabilities of artificially synthesized DNA ultra-thin films. Fully covered DNA ultra-thin films on a silica substrate were fabricated by the silica-assisted growth method and those samples were then incubated in various chemicals and physical conditions. The DNA ultra-thin films showed high maintainability under those harsh conditions and these results would aid to facilitate the use of artificial DNA ultra-thin films in advanced research areas such as biophotonics and bioelectronics.

► The structural and functional stabilities of DNA structures are discussed.
► DNA structures were fabricated by the silica-assisted growth method.
► DNA samples were then incubated in various chemicals and physical conditions.
► DNA ultra-thin films showed high maintainability under those harsh conditions.
► Our results aid to facilitate the use of DNA structures in advanced research area.