Structures and physical properties of the cocrystals of adefovir dipivoxil with dicarboxylic acids

► Cocrystallization of adefovir dipivoxil and suberic or succinic acid. ► H-bonding between the adenine (adefovir dipivoxil) and the carboxylic acid (suberic or succinic acid). ► Improved thermal stability and aqueous solubility through cocrystal formation.