کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1807538 | 1025265 | 2007 | 9 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Diffusion tensor MRI to investigate dementias: a brief review Diffusion tensor MRI to investigate dementias: a brief review](/preview/png/1807538.png)
Diffusion tensor magnetic resonance imaging (DT-MRI) is a powerful quantitative technique with the ability to detect in vivo microscopic characteristics and abnormalities of brain tissue. It has been successfully applied to a number of neurological conditions, such as stroke, multiple sclerosis and brain tumors, providing information otherwise inaccessible on the pathological substrates. DT-MRI has also been used to study patients with cognitive decline, mainly those with Alzheimer's disease. Several image-analysis approaches have been employed, including region of interest, histogram, voxel-based analyses and DT-MRI-based tractography. Specific patterns of spatial distribution of tissue damage and correlations with neuropsychological measures have been reported. This review focuses on the use of DT-MRI to investigate dementias. The main clinical results and the different methods of image analysis will be overviewed and discussed.
Journal: Magnetic Resonance Imaging - Volume 25, Issue 6, July 2007, Pages 969–977