کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
18162 42713 2007 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Microbial transformation of the bioactive sesquiterpene, cyclonerodiol, by the ascomycete Penicillium sp. and the actinomycete Streptomyces sp.
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Microbial transformation of the bioactive sesquiterpene, cyclonerodiol, by the ascomycete Penicillium sp. and the actinomycete Streptomyces sp.
چکیده انگلیسی

Biological transformation of the bioactive sesquiterpene, cyclonerodiol (1), isolated from marine-derived fungus Myrothecium sp., was studied. Preparative-scale fermentation of 1 with marine-derived fungus Penicillium sp. resulted in the isolation of a new glycosidic metabolite, 7-O-(β-d-mannopyranosyl)cyclonerodiol (2). Fermentation of 1 for 2 weeks with a marine isolate of the actinomycete bacteria Streptomyces sp. also afforded two oxidized geometrical isomers, 10(Z)- and 10(E)-cyclonerotriols (3, 4). The stereostructure of the metabolites obtained was assigned on the basis of detailed spectroscopic data analyses and chemical reaction.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Enzyme and Microbial Technology - Volume 40, Issue 5, 3 April 2007, Pages 1188–1192
نویسندگان
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